Rice Bran Wax Fatty Acid Methyl Esters (INCI: *Methyl Palmitate, Methyl Behenate, Methyl Lignocerate*) 

• Chemical Family: Fatty Acid Methyl Esters (FAME)
• Recommended Use: Emollient for skincare, haircare, and cosmetic formulations.
• Manufacturer/Supplier: Pure Check India Pvt. Ltd. Lab No 2, Bhare Industrial Estate, Gat 405/9, Bhare, Tal. Mulshi, Pune – 412 115.
• Emergency Contact: 9890300363/7499224350

SECTION 2: HAZARD IDENTIFICATION

• GHS Classification:
  • Skin Irritation: Category 2 (H315) — based on neat substances.
  • Eye Irritation: Category 2A (H319) — *based on neat substance*.
  • Not classified for acute toxicity, flammability, or environmental hazards.
• Signal Word: Warning
• Hazard Statements:
  • H315: Causes skin irritation.
  • H319: Causes serious eye irritation.
• Precautionary Statements:
  • P264: Wash skin thoroughly after handling.
  • P280: Wear protective gloves/eye protection.
  • P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes.

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 

Note: Complies with EU Cosmetics Regulation (EC) No 1223/2009 and FDA guidelines for cosmetic ingredients. 

SECTION 4: FIRST-AID MEASURES 

• Skin Contact: Wash with mild soap and water. Apply moisturizer if irritation occurs.
• Eye Contact: Flush with water for 15 minutes. Seek medical attention if irritation persists.

SECTION 8: EXPOSURE CONTROLS/PPE 

• PPE: Nitrile gloves, safety goggles, and lab coat when handling raw material.
• Work Hygiene: Avoid inhalation of dust/aerosols during processing.

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 

• Appearance: White – Off-white waxy solid.
• Odor: Faint, characteristic.
• Melting Point: 35–40°C (emollient texture when formulated).
• Solubility: Soluble in Ethyl acetate, Dispersible in oils and cosmetic esters (e.g., caprylic/capric triglyceride).

SECTION 11: TOXICOLOGICAL INFORMATION 

• Dermal Safety:
  • Non-comedogenic and low irritation potential at typical use levels (1–10% in final product).
  • No evidence of sensitization in human repeat insult patch tests (HRIPT)*. 
  • Oral Toxicity: LD50 > 2000 mg/kg (rat) — low acute toxicity.

(Include relevant study data if available.)

SECTION 12: ECOLOGICAL INFORMATION

– Biodegradability: Expected to be readily biodegradable. 

SECTION 15: REGULATORY INFORMATION

– Complies with: 

  – EU Cosmetics Regulation (EC) No 1223/2009. 

  – FDA 21 CFR §700–740 (cosmetic ingredient safety). 

  – Listed in Cosing (Cosmetic Ingredient Database). 

– Vegan/Non-GMO: Confirm based on sourcing (if applicable). 

SECTION 16: OTHER INFORMATION

– Cosmetic Performance: 

  – Acts as a occlusive emollient, improving skin barrier function and reducing transepidermal water loss (TEWL). 

  – Compatible with liposomes, anhydrous formulations, and emulsified systems. 

– Formulation Tips: 

  – Blend with lighter esters (e.g., ethylhexyl palmitate) to adjust melting point and texture. 

  – Use in creams, balms, lipsticks, and hair conditioners. 

Key Revisions for Cosmetic Use: 

1. INCI Nomenclature: Added for regulatory compliance.
2. Toxicology: Emphasized safety at typical use levels and non-comedogenic claims.
3. Application Notes: Included performance benefits for formulators.
4. Regulatory Focus: Aligned with EU/FDA cosmetic standards.

Disclaimer:

This MSDS is for the raw material. Final product safety must be validated through stability, compatibility, and preservative efficacy testing. Conduct patch testing for sensitive populations. 

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